Steve, your USB mixer will not help, because the keyboard doesn't actually produce any audio, (it's a USB MIDI controller) so there's nothing for the mixer to work with.
Do you by any chance have loads of other USB stuff connected to your PC? That might influence the performance of the controller. As steve says, ASIO4ALL is worth a try - I've used it with reasonable success on a really old creaky PC to improve latency.
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